Hello crossword solvers! Today let's find the answer to the clue Sampras with five U.S. Open wins from the USA Today crossword. After we've gathered any other hints from the USA Today crossword puzzle and all possible helpful and relevant information from other sources, we are ready to solve the clue Sampras with five U.S. Open wins. The answer we found for the clue Sampras with five U.S. Open wins is: